Anastasiou Diane M, Morgan Margie, Ruane Peter J, Steenbergen Judith N, Katz Bradley D, Alder Jeff D, Thorne Grace M
Cubist Pharmaceuticals Inc., Lexington, MA 02421, USA.
Diagn Microbiol Infect Dis. 2008 Jul;61(3):339-42. doi: 10.1016/j.diagmicrobio.2008.01.012. Epub 2008 Mar 4.
The in vitro activity of daptomycin was evaluated against 360 multidrug-resistant Staphylococcus aureus isolates (including hospital-acquired isolates) and multidrug-susceptible community-acquired methicillin-resistant S. aureus with known virulence genes. All isolates were inhibited at <or=1 microg/mL, suggesting that daptomycin has excellent activity against both hospital-acquired and community-acquired S. aureus isolates.
对达托霉素的体外活性进行了评估，受试对象为360株多重耐药金黄色葡萄球菌分离株（包括医院获得性分离株）以及具有已知毒力基因的多重药物敏感的社区获得性耐甲氧西林金黄色葡萄球菌。所有分离株在浓度≤1微克/毫升时均受到抑制，这表明达托霉素对医院获得性和社区获得性金黄色葡萄球菌分离株均具有出色的活性。
Zotero 插件