1987 - 2003年马萨诸塞州男性消防员的癌症发病率。

Cancer incidence among male Massachusetts firefighters, 1987-2003.

作者信息

Kang Dongmug, Davis Letitia K, Hunt Phillip, Kriebel David

机构信息

Department of Preventive and Occupational Medicine, Pusan National University School of Medicine, Busan, Korea.

出版信息

Am J Ind Med. 2008 May;51(5):329-35. doi: 10.1002/ajim.20549.

DOI:10.1002/ajim.20549

PMID:18306327

Abstract

BACKGROUND

Firefighters are known to be exposed to recognized or probable carcinogens. Previous studies have found elevated risks of several types of cancers in firefighters.

METHODS

Standardized morbidity odds ratio (SMORs) were used to evaluate the cancer risk in white, male firefighters compared to police and all other occupations in the Massachusetts Cancer Registry from 1986 to 2003. Firefighters and police were identified by text search of the usual occupation field. All other occupations included cases with identifiable usual occupations not police or firefighter. Control cancers were those not associated with firefighters in previous studies.

RESULTS

Risks were moderately elevated among firefighters for colon cancer (SMOR = 1.36, 95% CI: 1.04-1.79), and brain cancer (SMOR = 1.90, 95% CI: 1.10-3.26). Weaker evidence of increased risk was observed for bladder cancer (SMOR = 1.22, 95% CI: 0.89-1.69), kidney cancer (SMOR = 1.34, 95% CI: 0.90-2.01), and Hodgkin's lymphoma (SMOR = 1.81, 95% CI: 0.72-4.53).

CONCLUSIONS

These findings are compatible with previous reports, adding to the evidence that firefighters are at increased risk of a number of types of cancer.

摘要

背景

众所周知，消防员会接触到已确认或可能的致癌物。先前的研究发现消防员患几种癌症的风险有所升高。

方法

使用标准化发病比值比（SMORs）来评估1986年至2003年马萨诸塞州癌症登记处中白人男性消防员相较于警察及所有其他职业的癌症风险。通过对通常职业领域进行文本搜索来识别消防员和警察。所有其他职业包括那些可识别的通常职业不是警察或消防员的病例。对照癌症是先前研究中与消防员无关的那些癌症。

结果

消防员患结肠癌（SMOR = 1.36，95%可信区间：1.04 - 1.79）和脑癌（SMOR = 1.90，95%可信区间：1.10 - 3.26）的风险适度升高。膀胱癌（SMOR = 1.22，95%可信区间：0.89 - 1.69）、肾癌（SMOR = 1.34，95%可信区间：0.90 - 2.01）和霍奇金淋巴瘤（SMOR = 1.81，95%可信区间：0.72 - 4.53）的风险增加证据较弱。