Marais Ben J
Department of Paediatrics and Child Health and the Desmond Tutu TB Centre, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa. bjmarais @sun.ac.za
Pediatr Pulmonol. 2008 Apr;43(4):322-9. doi: 10.1002/ppul.20787.
Tuberculosis (TB) control poses one of the major global health challenges in the new millennium. Children in TB-endemic areas suffer severe TB related morbidity and mortality, despite the availability of cheap and effective TB treatment. However, providing an accurate TB diagnosis together with access to supervised, child friendly treatment remains difficult in resource-limited settings. This review provides a broad overview of recent advances related to child TB, focusing on intra-thoracic disease manifestations. It summarizes current understanding of TB epidemiology, disease prevention, diagnosis and treatment, but also introduces novel concepts for further discussion and future evaluation.
结核病控制是新千年全球主要的健康挑战之一。尽管有廉价且有效的结核病治疗方法，但结核病流行地区的儿童仍遭受与结核病相关的严重发病和死亡。然而，在资源有限的环境中，提供准确的结核病诊断以及获得有监督的、适合儿童的治疗仍然很困难。本综述全面概述了与儿童结核病相关的最新进展，重点关注胸内疾病表现。它总结了目前对结核病流行病学、疾病预防、诊断和治疗的理解，同时也引入了新的概念以供进一步讨论和未来评估。
