Tsuchida S, Usui R, Usui R, Muramatsu U, Ejima H, Ikemoto S
Department of Legal Medicine and Human Genetics, Jichi Medical School, Tochigi-ken, Japan.
J Vet Med Sci. 1991 Feb;53(1):19-21. doi: 10.1292/jvms.53.19.
Autoantibodies and erythrocyte membrane proteins were analyzed in a case of a dog with autoimmune hemolytic anemia (AIHA). In crisis phase, antiglobulin test was positive. The eluate from the erythrocytes of the dog with AIHA gave agglutination against autologus erythrocytes. Immunoglobulin subclasses in the eluate were revealed to be IgG and IgA by the double diffusion test. Comparing the SDS polyacrylamide gel electrophoretic patterns of erythrocyte membrane proteins between the crisis and remission phases, there was a change in the protein on protein 4.1 region. However, there were no changes in blood group typings in two phases.
