Duhem-Tonnelle V, Duhem R, Allaoui M, Chastanet P, Assaker R
Clinique de neurochirurgie, CHRU de Lille, place de Verdun, 59037 Lille, France.
Neurochirurgie. 2008 Feb;54(1):46-52. doi: 10.1016/j.neuchi.2008.01.005. Epub 2008 Mar 4.
Treatment of cervical spine fracture in patients with ankylosing spondylitis is difficult. Biomechanical changes related to ossified ankylosing spondylitis spine make cervical spine fractures highly unstable. They cover the entire width of the spine inducing multidirectional instability and the risk of neurological injuries. Treatment is more difficult that in the nonossified spine. Different treatments have been proposed including anterior stabilization, posterior stabilization, or both.
We reviewed retrospectively six cases of cervical fracture dislocation in patients with ankylosing spondylitis.
There were five cases of C6C7 fracture dislocation and one case of C4C5 fracture dislocation. Four patients had neurological impairment at diagnosis. All patients underwent surgery. Two had anterior stabilization: one patient died and the other achieved bone healing. Four patients had anterior and posterior stabilization combined with a cervical brace for three months, for two and a halo cast for two, others because of persistent instability, with neurological injury in one. A neurological improvement was obtained in four patients. One patient was lost to follow-up.
Surgical management of selected patients with ankylosing spondylitis and cervical spine fractures is challenging. Combined anterior and posterior stabilization should be considered for these fractures. A cervical brace must be associated with surgical treatment. With appropriate management, outcome can be favorable.
强直性脊柱炎患者颈椎骨折的治疗较为困难。与强直性脊柱炎脊柱骨化相关的生物力学改变使颈椎骨折高度不稳定。它们覆盖脊柱的整个宽度,导致多方向不稳定以及神经损伤风险。治疗比非骨化脊柱的情况更困难。已提出不同的治疗方法,包括前路稳定、后路稳定或两者结合。
我们回顾性分析了6例强直性脊柱炎患者颈椎骨折脱位的病例。
有5例C6C7骨折脱位和1例C4C5骨折脱位。4例患者在诊断时有神经功能障碍。所有患者均接受了手术。2例行前路稳定术:1例患者死亡,另1例实现骨愈合。4例患者行前路和后路联合稳定术,并佩戴颈托3个月,2例佩戴头颈胸石膏2个月,其他患者因持续不稳定,其中1例有神经损伤。4例患者神经功能得到改善。1例患者失访。
对选定的强直性脊柱炎合并颈椎骨折患者进行手术治疗具有挑战性。对于这些骨折应考虑联合前路和后路稳定术。手术治疗必须结合颈托。通过适当的处理,预后可能良好。