Hexeberg Sofie, Lindberg Fedon A
Dr. Fedon Lindbergs Klinikk, Sjølyst Medisinske Senter, Karenslyst allé 16 D, 0278 Oslo.
Tidsskr Nor Laegeforen. 2008 Feb 14;128(4):443-5.
A 61-year-old overweight woman had been diagnosed with diabetes mellitus, hypertension and hypothyreosis. Treatment with antidiabetic and antihypertensive medication and thyroxine had been started. Blood sugar had been increasing despite medication and she had started using insulin. In 2003 she used 150 IE insulin per day. She tried hard to adhere to a recommended diet, but gradually became fatter, maximum weight was 120 kg. She started on a low carbohydrate diet on her own and lost 14 kg during 5 months. She had some hypoglycemic episodes and sought advice at Dr. Fedon Lindberg's Clinic. Her low carbohydrate diet was continued, endurance exercise was included, medication with metformin was started and during 8 months she was off insulin and showed much lower blood sugar values than before. She lost 14 kg during this period. She was motivated for loosing more weight and starter on a VLCD (very low caloric diet). She lost another 9 kg on this diet. She than started regular resistance training and her weight stabilized on 80 kg. Her HbA1c value has been reduced from 8.9 to 5.4% and her total/HDL cholesterol ratio has been reduced from 5.4 to 1.7. Her C-peptide value increased in the period when insulin was reduced, but is now reduced to 700 pmol/L. Micro-CRP has been reduced from 9.0 mg/L to 0.4 mg/L. With a low carbohydrate diet and exercise this woman no longer has diabetes or severe overweight. It is our opinion that many patients with type 2 diabetes can manage without medication (especially insulin) by reducing the intake of carbohydrates considerably.
一名61岁的超重女性被诊断出患有糖尿病、高血压和甲状腺功能减退症。已开始使用抗糖尿病、抗高血压药物和甲状腺素进行治疗。尽管用药，血糖仍在升高，她开始使用胰岛素。2003年，她每天使用150国际单位胰岛素。她努力遵循推荐的饮食，但逐渐变得更胖，最大体重为120公斤。她自行开始低碳水化合物饮食，在5个月内减重14公斤。她出现了一些低血糖发作，并在费登·林德伯格医生的诊所寻求建议。她继续低碳水化合物饮食，增加耐力运动，开始服用二甲双胍，8个月后她停用了胰岛素，血糖值比以前低得多。在此期间她减重14公斤。她有动力进一步减重，开始采用极低热量饮食（VLCD）。通过这种饮食她又减重9公斤。然后她开始进行常规抗阻训练，体重稳定在80公斤。她的糖化血红蛋白（HbA1c）值从8.9%降至5.4%，总胆固醇/高密度脂蛋白胆固醇比值从5.4降至1.7。在胰岛素减少期间她的C肽值升高，但现在降至700皮摩尔/升。超敏C反应蛋白（Micro-CRP）从9.0毫克/升降至0.4毫克/升。通过低碳水化合物饮食和运动，这名女性不再患有糖尿病或严重超重。我们认为，许多2型糖尿病患者通过大幅减少碳水化合物摄入量可以无需药物（尤其是胰岛素）治疗。
