de Soto-Perera M A
Department of Analytical Chemistry, Marion Merrell Dow Research Institute, Cincinnati, Ohio 45215.
Pharm Res. 1991 May;8(5):615-8. doi: 10.1023/a:1015856724045.
Two nonsuppressed, single-column ion chromatographic procedures have been developed and validated for the determination of the total sodium and chloride ion content in lyophilized vials containing teicoplanin. The assays served to determine the amount of sodium chloride added to the vials and to estimate the amount of sodium associated with the teicoplanin molecule.
已开发并验证了两种非抑制单柱离子色谱法,用于测定含有替考拉宁的冻干瓶中的总钠离子和氯离子含量。这些测定方法用于确定添加到瓶中的氯化钠量,并估计与替考拉宁分子相关的钠量。