Morehouse Kim M, Nyman Patricia J, McNeal Timothy P, Dinovi Michael J, Perfetti Gracia A
Food and Drug Administration-CFSAN, College Park, MD 20740, USA.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2008 Mar;25(3):259-64. doi: 10.1080/02652030701552949.
Furan is a suspected human carcinogen that is formed in some processed foods at low ng per g levels. Recent improvements in analytical methodology and scientific instrumentation have made it possible to accurately measure the amount of furan in a wide variety of foods. Results from analysis of more than 300 processed foods are presented. Furan was found at levels ranging from non-detectable (LOD, 0.2-0.9 ng g(-1)) to over 100 ng g(-1). Exposure estimates for several adult food types were calculated, with brewed coffee being the major source of furan in the adult diet (0.15 microg kg(-1) body weight day(-1)). Estimates of mean exposure to furan for different subpopulations were calculated. For consumers 2 years and older, the intake is estimated to be about 0.2 microg kg(-1) body weight day(-1).
呋喃是一种疑似人类致癌物,在一些加工食品中以每克纳克级的低含量形成。近期分析方法和科学仪器的改进使得准确测量各种食品中呋喃的含量成为可能。本文展示了对300多种加工食品的分析结果。发现呋喃的含量范围从不可检测(检测限为0.2 - 0.9纳克/克)到超过100纳克/克。计算了几种成人食品类型的暴露量估计值,其中煮制咖啡是成人饮食中呋喃的主要来源(0.15微克/千克体重/天)。计算了不同亚人群对呋喃的平均暴露量估计值。对于2岁及以上的消费者,摄入量估计约为0.2微克/千克体重/天。