模块化RNA升温。

Modular RNA heats up.

作者信息

Shamovsky Ilya, Nudler Evgeny

机构信息

Department of Biochemistry, New York University School of Medicine, New York, NY 10016, USA.

出版信息

Mol Cell. 2008 Feb 29;29(4):415-7. doi: 10.1016/j.molcel.2008.02.001.

DOI:10.1016/j.molcel.2008.02.001

PMID:18313380

Abstract

In this issue of Molecular Cell, Mariner et al. (2008) demonstrate that Alu RNA from a human SINE represses RNA polymerase II transcription during heat shock. This noncoding RNA is the first example of a "protein-like" transcription factor with a distinct modular architecture.

摘要

在本期《分子细胞》杂志中，马里纳等人（2008年）证明，来自人类短散在核元件（SINE）的Alu RNA在热休克期间会抑制RNA聚合酶II转录。这种非编码RNA是具有独特模块化结构的“类蛋白质”转录因子的首个实例。