Lin Ching-Chia, Tsai Ming-Hsui, Huang Chiu-Chen, Hua Chun-Hung, Tseng Hsian-Chang, Huang Shih-Tzu
Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan.
Am J Otolaryngol. 2008 Mar-Apr;29(2):94-100. doi: 10.1016/j.amjoto.2007.03.002.
The aim of the present study was to analyze the clinical presentation, histopathology, and complications of parotid tumors, as well as the management of malignant parotid tumors.
We retrospectively reviewed the medical records of 271 patients who underwent parotidectomy from August 1996 to July 2006. Data including age, sex, clinical signs and symptoms, histologic findings, complications, malignant tumor stage, and prognosis were collected from medical charts.
Of the 271 patients who underwent parotidectomy, 229 (85%) had benign tumors, 33 (12%) had malignant tumors, and 9 had chronic inflammatory disease (3%). The most common benign tumor was pleomorphic adenoma (51%), and the most common malignant tumor was mucoepidermoid carcinoma (3%). The 5-year overall survival rate was 42%, and the disease-specific survival rate for malignant tumor was 72%. Only disease stage was the statistically significant prognostic factor of malignancy. The most common complication of parotidectomy was transient facial palsy (18%).
Standardized superficial and total parotidectomy are safe procedures for treating parotid tumors. Management of malignant tumors depends on tumor stage and histologic grade. Advanced tumor stage is a predictor of poor outcome.
本研究旨在分析腮腺肿瘤的临床表现、组织病理学及并发症，以及恶性腮腺肿瘤的治疗方法。
我们回顾性分析了1996年8月至2006年7月期间接受腮腺切除术的271例患者的病历。从病历中收集了包括年龄、性别、临床症状和体征、组织学检查结果、并发症、恶性肿瘤分期及预后等数据。
在接受腮腺切除术的271例患者中，229例（85%）为良性肿瘤，33例（12%）为恶性肿瘤，9例（3%）为慢性炎症性疾病。最常见的良性肿瘤是多形性腺瘤（51%），最常见的恶性肿瘤是黏液表皮样癌（3%）。5年总生存率为42%，恶性肿瘤的疾病特异性生存率为72%。仅疾病分期是恶性肿瘤具有统计学意义的预后因素。腮腺切除术最常见的并发症是暂时性面神经麻痹（18%）。
标准化的浅叶及全腮腺切除术是治疗腮腺肿瘤的安全手术方法。恶性肿瘤的治疗取决于肿瘤分期和组织学分级。肿瘤晚期是预后不良的预测因素。
