Savvas Ioannis, Papazoglou Lysimachos G, Kazakos George, Anagnostou Tilemahos, Tsioli Vassiliki, Raptopoulos Dimitris
Companion Animal Clinic, Department of Clinical Sciences, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 11 S. Voutyra Street, 54627, Thessaloniki, Greece.
J Am Anim Hosp Assoc. 2008 Mar-Apr;44(2):60-6. doi: 10.5326/0440060.
A blind, placebo-controlled clinical trial was performed to evaluate the postoperative analgesic effect of preoperative infiltration of the incision site with bupivacaine in dogs undergoing celiotomy. Sixty dogs were randomly allocated into four groups: preoperative bupivacaine, postoperative bupivacaine, preoperative saline, and postoperative saline. All dogs were premedicated with acepromazine and meperidine; then they were anesthetized with thiopentone and isoflurane. Each group received either bupivacaine or normal saline before midline incision or just before skin closure. After surgery, pain scores were assigned using a numerical rating scale. Preoperative bupivacaine was associated with significantly lower pain scores and a significantly lower need for opioid administration. The authors conclude that a preoperative incisional block with bupivacaine seems to be a useful adjunct for controlling pain after celiotomy in dogs.
进行了一项双盲、安慰剂对照临床试验，以评估在接受剖腹术的犬中，术前在切口部位浸润布比卡因的术后镇痛效果。60只犬被随机分为四组：术前布比卡因组、术后布比卡因组、术前生理盐水组和术后生理盐水组。所有犬均用乙酰丙嗪和哌替啶进行术前用药；然后用硫喷妥钠和异氟烷麻醉。每组在中线切口前或即将缝合皮肤前接受布比卡因或生理盐水。术后，使用数字评分量表进行疼痛评分。术前布比卡因组的疼痛评分显著更低，且对阿片类药物的需求也显著更低。作者得出结论，术前用布比卡因进行切口阻滞似乎是控制犬剖腹术后疼痛的一种有用辅助方法。
