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[巨噬细胞样细胞系MMC-1生物学特性的延时显微电影分析]

[Time-lapse microcinematographical analysis of the biological characteristics of a macrophage-like cell line--MMC-1].

作者信息

Wang R

机构信息

Institute of Basic Medical Sciences, Beijing.

出版信息

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1991 Feb;13(1):24-8.

PMID:1831697
Abstract

By using time-lapse microcinematography, we recorded and conducted an analysis of the macrophage-like cell line MMC-1, including observations of the spreading, polarity, contact inhibition and mitosis common to cultured cells as well as the properties of phagocytosis and rosette formation unique to macrophage. We also found an MMC-1 cell which, after feeding, still stretched its finger-like filopodia towards surrounding red blood cells. The filopodia extended as red blood cells moved towards them. At the point of contact, red blood cell fragments were seen moving towards the cell body along the filopodia; a kind of cytolysis was progressing.

摘要

通过延时显微摄影术,我们记录并分析了巨噬细胞样细胞系MMC-1,包括对培养细胞常见的铺展、极性、接触抑制和有丝分裂的观察,以及巨噬细胞特有的吞噬作用和玫瑰花结形成特性。我们还发现了一个MMC-1细胞,在摄取营养后,它仍向周围的红细胞伸出指状丝状伪足。随着红细胞向丝状伪足移动,丝状伪足不断延伸。在接触点处,可以看到红细胞碎片沿着丝状伪足向细胞体移动;一种细胞溶解正在进行。

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