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[工业生物技术工作者中支气管肺病理学预防的当前方面]

[Current aspects of prevention of bronchopulmonary pathology among industrial biotechnology workers].

作者信息

Artamonova V G, Svitina N N

出版信息

Gig Tr Prof Zabol. 1991(3):31-3.

PMID:1831785
Abstract

The growing scope of biotechnologic enterprises now in process necessitates provision of safe labour conditions and health protecting measures. It was suggested that the biologic factor inherent in modern industries can provoke bronchopulmonary pathologic conditions. The performed clinical studies of the immunocompetent system state in workers revealed adaptational changes in the form of phagocytic functional activity and increase in the immune complexes circulating in blood serum. Bronchoallergic patients exhibited more profound immunity disorders with a considerable decrease in T-suppressors and peripheral blood eosinophil growth. Preventive treatment with the natrium nucleinate immunomodulator was performed with a positive result.

摘要

目前正在发展的生物技术企业规模不断扩大,因此必须提供安全的劳动条件和健康保护措施。有人认为,现代工业中固有的生物因素可能引发支气管肺部病理状况。对工人免疫活性系统状态进行的临床研究表明,吞噬功能活性形式的适应性变化以及血清中循环免疫复合物增加。支气管过敏患者表现出更严重的免疫紊乱,T抑制细胞显著减少,外周血嗜酸性粒细胞增多。用核酸钠免疫调节剂进行预防性治疗,取得了积极效果。

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