Kuzina L E, Sadikova N V, Nikolaev V L, Malyshev N A, Zverev V V, Kuzin S N
Vopr Virusol. 2008 Jan-Feb;53(1):41-4.
A regional external quality assessment (EQA) system for determining anti-hepatitis C virus (HCV) was developed and introduced. For this, a control panel comprising 14 samples with anti-HCV and 6 samples without anti-HCV was tested in the reference laboratory of Moscow Infectious Hospital One. A total of 6 sessions were conducted with the participation of 8 laboratories. The regional EQA system covering a limited number of laboratories was shown to significantly improve the quality of detection of hepatitis C virus antibodies. The optimal multiplicity of sessions for the developed EQA system was ascertained to be once fortnight. It is possible to define the current rating of screening laboratories in the sensitivity criterion and to elaborate address organizational-and-methodic measures according to the results of control tests.
开发并引入了一种用于测定抗丙型肝炎病毒（HCV）的区域外部质量评估（EQA）系统。为此，在莫斯科第一传染病医院的参考实验室对一个由14份含抗HCV样本和6份不含抗HCV样本组成的对照样本组进行了检测。共有8个实验室参与，总共进行了6次检测。结果表明，覆盖有限数量实验室的区域EQA系统显著提高了丙型肝炎病毒抗体检测的质量。已确定所开发的EQA系统的最佳检测频率为每两周一次。可以根据灵敏度标准确定筛查实验室的当前评级，并根据对照检测结果制定针对性的组织和方法措施。
