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[冠状动脉搭桥术后患者一氧化氮合成的特点]

[The peculiarties of nitric oxide synthesis in patients after coronary bypass surgery].

作者信息

Bulanova E L, Drapkina O M, Kutepov Iu S, Ivashkin V T

出版信息

Klin Med (Mosk). 2007;85(12):26-30.

PMID:18318162
Abstract

Nitric oxide (NO) participates in many physiological processes including those taking place in the cardiovascular system. The peculiarities of NO synthesis in patients after coronary bypass surgery were studied. The systems of NO generation responded in different ways. Changes in the levels of end-products of NO metabolism may be used as an additional prognostic criterion of the course of the postoperative period. The study found a direct correlation between the levels of end-products of NO metabolism and left ventricular ejection fraction as well as a reverse correlation between the level of end-products of NO metabolism and atherogenic lipids.

摘要

一氧化氮(NO)参与许多生理过程,包括发生在心血管系统中的那些过程。研究了冠状动脉搭桥手术后患者体内NO合成的特点。NO生成系统的反应各不相同。NO代谢终产物水平的变化可用作术后病程的额外预后标准。该研究发现NO代谢终产物水平与左心室射血分数之间存在直接相关性,以及NO代谢终产物水平与致动脉粥样硬化脂质之间存在负相关。

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