Toxicodynamic assumptions in ecotoxicological hazard models.
作者信息
Ashauer Roman, Brown Colin D
机构信息
Eawag-Aquatic Research, Uberlandstrasse 133, 8600 Dübendorf, Switzerland.
出版信息
Environ Toxicol Chem. 2008 Aug;27(8):1817-21. doi: 10.1897/07-642. Epub 2008 Mar 4.
DOI:10.1897/07-642
PMID:18318593
Abstract
Existing toxicokinetic and toxicodynamic models and dynamic formulations of popular ecotoxicological concepts (e.g., the critical body residue concept) are examined. Their underlying assumptions about speed of recovery and thresholds are clarified, and a rigorous mathematical treatment shows that they can all be placed within a unifying framework. Such analysis aids in the selection of appropriate ecotoxicological models.
摘要
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