Onwasigwe E N, Ezegwui I R, Onwasigwe C N, Aghaji A E
Department of Ophthalmology, University of Nigeria Teaching Hospital, Enugu, Nigeria.
Ann Trop Paediatr. 2008 Mar;28(1):49-52. doi: 10.1179/146532808X270671.
To review the management of congenital glaucoma, bearing in mind the limited facilities available in developing countries.
The medical records of children aged < or = 3 years with primary congenital glaucoma seen at two teaching hospitals and one private eye hospital in Enugu, Nigeria over a 5-year period were reviewed retrospectively. All the children underwent trabeculectomy without use of anti-metabolites.
Fifty-seven eyes of 32 patients (5 unilateral, 26 bilateral) were reviewed. Pre-operatively, 63.2% of the eyes had a corneal diameter of 12-15 mm. After surgery, the number with corneal haziness decreased from 25 (43.8%) to 15 (26.4%) (p=0.05). The mean (SD) pre-operative intra-ocular pressure (IOP) was 28.3 (7.5) mmHg and the mean post-operative IOP was 17 (5.6) mmHg (p=0.001).
When facilities for other treatment modalities are not available, primary trabeculectomy without the use of anti-metabolites can be employed to manage primary congenital glaucoma.
鉴于发展中国家可用设施有限，回顾先天性青光眼的治疗方法。
回顾性分析尼日利亚埃努古的两家教学医院和一家私立眼科医院在5年期间接诊的年龄≤3岁的原发性先天性青光眼患儿的病历。所有患儿均接受了未使用抗代谢药物的小梁切除术。
对32例患者（5例单眼，26例双眼）的57只眼进行了评估。术前，63.2%的眼睛角膜直径为12 - 15毫米。术后，角膜混浊的眼睛数量从25只（43.8%）降至15只（26.4%）（p = 0.05）。术前平均（标准差）眼压（IOP）为28.3（7.5）mmHg，术后平均眼压为17（5.6）mmHg（p = 0.001）。
当没有其他治疗方式所需的设施时，可采用不使用抗代谢药物的原发性小梁切除术来治疗原发性先天性青光眼。
