儿童鱼鳞病样红皮病综合征

KID syndrome.

作者信息

Abdollahi Ali, Hallaji Zahra, Esmaili Nafiseh, Valikhani Mahin, Barzegari Masoumeh, Akhyani Maryam, Toosi Siavash, Miresmaili Alireza

机构信息

Department of Ophthalmology, Farabi Hospital, Tehran University of Medical Sciences.

出版信息

Dermatol Online J. 2007 Oct 13;13(4):11.

PMID:18319008

Abstract

KID syndrome is a rare congenital disorder characterized by keratitis, ichthyosis, and deafness. We have described a 4-year-old girl who is treated with bland emollients and topical keratolytics such as urea and surprisingly observed marked improvement in skin hyperkeratosis and palmoplantar keratoderma. We think that along with urgent ophthalmologic and otolaryngologic measures, simple topical therapies may improve skin condition in KID syndrome precluding the possible hazards of systemic retinoid therapy.

摘要

KID综合征是一种罕见的先天性疾病，其特征为角膜炎、鱼鳞病和耳聋。我们描述了一名4岁女孩，她接受了温和润肤剂和尿素等外用角质松解剂的治疗，令人惊讶的是，皮肤过度角化和掌跖角皮病有明显改善。我们认为，除了紧急的眼科和耳鼻喉科措施外，简单的局部治疗可能会改善KID综合征的皮肤状况，避免全身使用维甲酸治疗可能带来的危害。