Perdereau F, Faucher S, Wallier J, Vibert S, Godart N
Department of Psychiatry for Adolescents and Young Adults, Université Paris-Descartes, Faculté de Médecine, Site Institut Mutualiste Montsouris (IMM), Paris, France.
Eat Weight Disord. 2008 Mar;13(1):1-13. doi: 10.1007/BF03327779.
To provide a critical review of the research on mood and anxiety disorders in relatives of individuals with anorexia nervosa (AN). In the first section, we explore methodological issues with these studies. In the second section, we present results.
A Medline search identified studies published on family history of mood and anxiety disorders in AN, and was complemented by a manual search. Only studies from 1980 to 2006 using strict diagnostic criteria for the disorders were included [Feighner and Halmi criteria for AN, Reasearch Diagnostic Criteria (RDC), Diagnostic and Statistical Manual of Mental Disorders - Third Edition - Revised (DSM-III-R) or DSM - Fourth Edition (DSM-IV) for anorexia and other disorders].
A review of the research methods used in the studies revealed a number of methodological problems. Therefore, we provide only a description of the prevalence of mood and anxiety disorders in relatives of individuals with AN.
In the light of the methodological issues uncovered, the value of the results of these studies and their implications for further study are considered.
对神经性厌食症（AN）患者亲属的情绪和焦虑障碍研究进行批判性综述。在第一部分，我们探讨这些研究的方法学问题。在第二部分，我们呈现研究结果。
通过医学在线数据库（Medline）检索关于AN患者亲属情绪和焦虑障碍家族史的已发表研究，并辅以手工检索。仅纳入1980年至2006年期间使用严格疾病诊断标准的研究[AN采用费格纳（Feighner）和哈尔米（Halmi）标准，其他疾病采用研究诊断标准（RDC）、《精神疾病诊断与统计手册》第三版修订本（DSM - III - R）或第四版（DSM - IV）]。
对这些研究所用研究方法的综述揭示了一些方法学问题。因此，我们仅描述AN患者亲属中情绪和焦虑障碍的患病率。
鉴于所发现的方法学问题，对这些研究结果的价值及其对进一步研究的意义进行了考量。
