Idrovo Alvaro Javier, Sanín Luz Helena
Instituto Nacional de Salud Pública, Ahuacatitlán, Cuernavaca, Morelos, México.
Biomedica. 2007 Dec;27(4):490-7.
Workers in floriculture are exposed to pesticides and other risk factors. Work in these occupational environments is suspected to be associated with adverse reproductive outcomes. However, epidemiological studies in Colombia, a country that has a long tradition with this occupation, have not been consistent or conclusive.
To quantify the effect of womens work in Colombian floriculture in the occurrence of spontaneous abortion, prematurity, and birth defects, using the results of two previous studies.
The results of two previous studies among Colombian floriculture worker populations were summarized with metaanalysis techniques. A critical evaluation of each of the studies identified potential biases and methodological limitations.
The pooled estimator of spontaneous abortion was 2.24 (95CI: 1.87-2.68); that of premature infant birth was 1.49 (95%CI: 0.91-2.43), and of birth defects 1.31 (95%CI: 1.95-1.64).
The analyses suggested that work in floriculture is associated with a higher occurrence of spontaneous abortion and birth defects. However, these effects are not necessarily associated with pesticide exposure. Other risk factors requiring further study are levels of physical activity and high temperature in greenhouses. Data from countries which have initiated occupations in floriculture more recently will add valuable evidence for this controversial association.
花卉种植工人接触农药及其他风险因素。在这些职业环境中的工作被怀疑与不良生殖结局有关。然而,在哥伦比亚这个在此职业方面有着悠久传统的国家,流行病学研究结果并不一致或具有决定性。
利用此前两项研究的结果,量化哥伦比亚花卉种植行业中女性工作与自然流产、早产和出生缺陷发生之间的关联。
运用荟萃分析技术总结此前两项针对哥伦比亚花卉种植工人群体的研究结果。对每项研究进行批判性评估,以确定潜在偏差和方法学局限性。
自然流产的合并估计值为2.24(95%置信区间:1.87 - 2.68);早产婴儿出生的合并估计值为1.49(95%置信区间:0.91 - 2.43),出生缺陷的合并估计值为1.31(95%置信区间:1.95 - 1.64)。
分析表明,花卉种植工作与自然流产和出生缺陷的较高发生率有关。然而,这些影响不一定与接触农药有关。其他需要进一步研究的风险因素包括体力活动水平和温室中的高温。来自最近才开始花卉种植职业的国家的数据将为这种有争议的关联增添有价值的证据。