Janzarik Wibke G, Müller Klaus, Lübbert Michael, Spreer Joachim, Trippel Michael, Uhlig Inge, Weiller Cornelius, Rauer Sebastian
Department of Neurology, Neurocenter, University of Freiburg, Freiburg, Germany.
J Neurooncol. 2008 Jun;88(2):217-9. doi: 10.1007/s11060-008-9554-0.
We present the rare case of a 31-year-old man who developed a germinoma 22 years after resection of a mature teratoma of the pineal region. The initial stereotactic biopsy showed a granulomatous inflammation, but no malignant cells. The correct diagnosis could only be confirmed in a second cerebral biopsy, allowing for proper treatment with radiation therapy. The need to consider metachronous germinoma in this setting is discussed.
我们报告了一例罕见病例，一名31岁男性在松果体区成熟畸胎瘤切除术后22年发生了生殖细胞瘤。最初的立体定向活检显示为肉芽肿性炎症，但未发现恶性细胞。只有在第二次脑活检中才能确诊，从而得以进行适当的放射治疗。本文讨论了在此种情况下考虑异时性生殖细胞瘤的必要性。
