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雷珠单抗(Lucentis)注射后玻璃体黄斑牵引的自发缓解

Spontaneous resolution of vitreomacular traction following ranibizumab (Lucentis) injection.

作者信息

Rouvas A, Petrou P, Ladas I, Neamonitou G, Vergados I

机构信息

Second Ophthalmology Department, University of Athens, Attikon Hospital, Athens, Greece.

出版信息

Eur J Ophthalmol. 2008 Mar-Apr;18(2):301-3. doi: 10.1177/112067210801800223.

Abstract

PURPOSE

Spontaneous resolution of vitreomacular traction syndrome in diabetic patients is a rare phenomenon that has been poorly described in the literature.

METHODS

Case presentation.

RESULTS

The authors present a case of spontaneous resolution of vitreomacular traction following intravitreal administration of ranibizumab.

CONCLUSIONS

In patients with vitreomacular traction syndrome and diabetic macular edema, the combination of the possible vitreous liquefaction and mechanical increase of vitreous volume caused by an intravitreal injection with a degree of reduction in retinal thickness caused by the effect of vascular endothelial growth factor inhibition could play a role in the resolution of vitreomacular traction.

摘要

目的

糖尿病患者玻璃体黄斑牵引综合征的自发缓解是一种罕见现象,在文献中鲜有描述。

方法

病例报告。

结果

作者报告1例玻璃体内注射雷珠单抗后玻璃体黄斑牵引自发缓解的病例。

结论

在玻璃体黄斑牵引综合征和糖尿病性黄斑水肿患者中,玻璃体内注射可能导致的玻璃体液化和玻璃体容积机械性增加,与血管内皮生长因子抑制作用所致的视网膜厚度一定程度的降低相结合,可能在玻璃体黄斑牵引的缓解中发挥作用。

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