安大略省南部养猪场中大肠杆菌O149:K91:F4的存在情况调查，以及抗菌药物的使用和与该血清群存在相关的风险因素。
An investigation of the presence of Escherichia coli O149:K91:F4 on pig farms in southern Ontario and the use of antimicrobials and risk factors associated with the presence of this serogroup.
作者信息
Amezcua Rocio, Friendship Robert M, Dewey Catherine E
机构信息
Department of Population Medicine, Ontario Veterinary College, University of Guelph.
出版信息
Can Vet J. 2008 Jan;49(1):39-45.
Abstract
Prevalence, causative factors, treatment, and preventative measures for O149:K91:F4 Escherichia coli infection of postweaning pigs was determined by using a cross-sectional study including 70 farms in Ontario. Surveys were distributed and samples cultured bacteriologically, resulting in 30% of farms testing positive to E. coli 0149:K91:F4. Possible causative factors, such as housing or nutrition, were not significantly different between positive and negative farms. Use of injectable antibiotics (P = 0.05) and zinc oxide (P = 0.003) was higher on E. coli O149:K91:K88 (F4)-positive farms. A higher level of biosecurity and the presence of other diseases may be associated with an increased risk of isolating E. coli O149:K91:F4 from weanling pigs.
摘要
通过对安大略省70个农场进行横断面研究，确定了断奶后仔猪感染O149:K91:F4大肠杆菌的流行情况、致病因素、治疗方法和预防措施。发放调查问卷并对样本进行细菌培养，结果显示30%的农场对O149:K91:F4大肠杆菌检测呈阳性。在阳性农场和阴性农场之间，诸如饲养环境或营养等可能的致病因素并无显著差异。在O149:K91:K88（F4）大肠杆菌阳性农场中，注射用抗生素（P = 0.05）和氧化锌（P = 0.003）的使用频率更高。更高水平的生物安全措施以及其他疾病的存在可能与从断奶仔猪中分离出O149:K91:F4大肠杆菌的风险增加有关。
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Anim Health Res Rev. 2005 Jun;6(1):17-39. doi: 10.1079/ahr2005105.
2
In utero infection with PRRS virus modulates cellular functions of blood monocytes and alveolar lung macrophages in piglets.
Vet Immunol Immunopathol. 2004 Jun;99(3-4):169-77. doi: 10.1016/j.vetimm.2004.02.008.
3
Antimicrobial resistance genes in enterotoxigenic Escherichia coli O149:K91 isolates obtained over a 23-year period from pigs.在23年期间从猪身上分离出的产肠毒素大肠杆菌O149:K91菌株中的抗菌抗性基因。
Antimicrob Agents Chemother. 2003 Oct;47(10):3214-21. doi: 10.1128/AAC.47.10.3214-3221.2003.
4
Response of early-weaned pigs to an enterotoxigenic Escherichia coli (K88) challenge when fed diets containing spray-dried porcine plasma or pea protein isolate plus egg yolk antibody, zinc oxide, fumaric acid, or antibiotic.早期断奶仔猪在采食含有喷雾干燥猪血浆或豌豆蛋白分离物加蛋黄抗体、氧化锌、富马酸或抗生素的日粮时，对产肠毒素大肠杆菌（K88）攻毒的反应。
J Anim Sci. 2003 Jul;81(7):1790-8. doi: 10.2527/2003.8171790x.
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J Appl Microbiol. 2003;94(6):1087-97. doi: 10.1046/j.1365-2672.2003.01937.x.
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