Niv Yaron
World J Gastroenterol. 2008 Mar 7;14(9):1313-7. doi: 10.3748/wjg.14.1313.
Good preparation before endoscopic procedures is essential for successful visualization. The small bowel is difficult to evaluate because of its length and complex configuration. A meta-analysis was conducted of studies comparing small bowel visualization by capsule endoscopy with and without preparation. Medical data bases were searched for all studies investigating the preparation for capsule endoscopy of the small bowel up to July 31, 2007. Studies that scored bowel cleanness and measured gastric and small bowel transit time and rate of cecum visualization were included. The primary endpoint was the quality of bowel visualization. The secondary endpoints were transit times and proportion of examinations that demonstrated the cecum, with and without preparation. Meta-analysis was performed with StatDirect Statistical software, version 2.6.1 (http://statsdirect.com). Eight studies met the inclusion criteria. Bowel visualization was scored as "good" in 78% of the examinations performed with preparation and 49% performed without (P<0.0001). There were no significant differences in transit times or in the proportion of examinations that demonstrated the cecum with and without preparation. Capsule endoscopy preparation improves the quality of small bowel visualization, but has no effect on transit times, or demonstration of the cecum.
内镜检查前的良好准备对于成功观察至关重要。由于小肠长度和复杂的结构，小肠难以评估。对比较有准备和无准备情况下胶囊内镜小肠观察的研究进行了荟萃分析。检索医学数据库，查找截至2007年7月31日所有关于小肠胶囊内镜检查准备的研究。纳入对肠道清洁度评分、测量胃和小肠转运时间以及盲肠观察率的研究。主要终点是肠道观察质量。次要终点是有准备和无准备情况下的转运时间以及显示盲肠的检查比例。使用StatDirect统计软件2.6.1版（http://statsdirect.com）进行荟萃分析。八项研究符合纳入标准。有准备的检查中78%肠道观察评分为“良好”，无准备的检查中为49%（P<0.0001）。有准备和无准备情况下的转运时间或显示盲肠的检查比例无显著差异。胶囊内镜检查准备可提高小肠观察质量，但对转运时间或盲肠显示无影响。
