Russell I Jon, Raphael Karen G
University Clinical Research Center, University of Texas Health Science Center, San Antonio, TX 78229-3900, USA.
CNS Spectr. 2008 Mar;13(3 Suppl 5):6-11. doi: 10.1017/s1092852900026778.
Fibromyalgia syndrome (FMS) presents with widespread soft tissue pain. Common comorbidities include severe insomnia, body stiffness, affective symptoms, irritable bowels, and urethral syndrome. A 1990 research classification depends on a history of widespread pain and prominent tenderness to palpation at 11 or more of 18 specific tender points. It is a criteria-based diagnosis rather than one by exclusion and can accompany other medical conditions. FMS occurs worldwide, and can present any age, but is most common in adult females. Although numerous studies and reviews contend that FMS may be caused by psychological stress such as sexual abuse, critical epidemiological review fails to support that concept. Existing data suggest that some individuals with FMS may have a dysregulated physiological stress response system that predates the onset of symptoms.
纤维肌痛综合征（FMS）表现为广泛的软组织疼痛。常见的合并症包括严重失眠、身体僵硬、情感症状、肠易激综合征和尿道综合征。1990年的一项研究分类取决于广泛疼痛的病史以及在18个特定压痛点中的11个或更多处有明显的触压痛。这是一种基于标准的诊断，而非排除性诊断，并且可能伴有其他疾病。FMS在全球范围内都有发生，可出现在任何年龄，但在成年女性中最为常见。尽管众多研究和综述认为FMS可能由心理压力如性虐待引起，但严格的流行病学综述并不支持这一观点。现有数据表明，一些FMS患者可能在症状出现之前就存在生理应激反应系统失调的情况。
