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妊娠期间的自身免疫性炎性肌病

Autoimmune inflammatory myopathy in pregnancy.

作者信息

Chopra Seema, Suri Vanita, Bagga Rashmi, Thami Meenakshi R, Sharma Aman, Bambery Pardeep

机构信息

Department of Gynecology and Obstetrics, PGIMER, Chandigarh, India.

出版信息

Medscape J Med. 2008 Jan 24;10(1):17.

Abstract

Autoimmune diseases such as systemic sclerosis, Wegner's granulomatosis, and polyarteritis nodosa are rarely seen in pregnancy, unlike systemic lupus erythematosus, whose association with pregnancy is well studied. Dermatomyositis is a protean disease that affects women in reproductive age. There are only a few case reports documenting the outcome of pregnancy in patients with dermatomyositis/polymyositis. The disease is usually considered to have an adverse effect on pregnancy. Fetal prognosis is guided by the severity of maternal disease and is usually good when the disease remains inactive during pregnancy.

摘要

自身免疫性疾病,如系统性硬化症、韦格纳肉芽肿病和结节性多动脉炎,在妊娠期间很少见,这与系统性红斑狼疮不同,后者与妊娠的关联已得到充分研究。皮肌炎是一种表现多样的疾病,影响育龄女性。仅有少数病例报告记录了皮肌炎/多肌炎患者的妊娠结局。该病通常被认为会对妊娠产生不利影响。胎儿预后取决于母体疾病的严重程度,当疾病在孕期保持不活动状态时,预后通常良好。

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