Souayah Nizar, Cros Didier, Stein T D, Chong Peter Siao Tick
Department of Neurology and Neurosciences, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA.
J Neurol Sci. 2008 Jul 15;270(1-2):184-8. doi: 10.1016/j.jns.2008.01.007. Epub 2008 Mar 5.
A 49-year-old man developed simultaneously a Guillain Barré Syndrome (GBS) and a nephrotic syndrome (NS). The patient relapsed twice, despite treatment with intravenous immunoglobulins (IVIg) after a full or partial recovery, and became resistant to IVIg. Renal biopsy revealed focal segmental glomerulosclerosis (FSGS). He responded to plasmapheresis and corticosteroids with simultaneous recovery of his GBS and NS, suggesting a common pathogenesis of the two conditions.
一名49岁男性同时患上了吉兰-巴雷综合征（GBS）和肾病综合征（NS）。尽管在完全或部分康复后接受了静脉注射免疫球蛋白（IVIg）治疗，该患者仍复发了两次，并对IVIg产生了耐药性。肾活检显示为局灶节段性肾小球硬化（FSGS）。他对血浆置换和皮质类固醇治疗有反应，GBS和NS同时康复，提示这两种病症有共同的发病机制。
