Microvascular function and ageing L-arginine, tetrahydrobiopterin and the search for the fountain of vascular youth.
作者信息
Heffernan Kevin S, Vieira Victoria J, Valentine Rudy J
机构信息
Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Champaign, IL, USA.
出版信息
J Physiol. 2008 Apr 15;586(8):2041-2. doi: 10.1113/jphysiol.2008.151381. Epub 2008 Mar 6.
Abstract
摘要
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本文引用的文献
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Ageing diminishes endothelium-dependent vasodilatation and tetrahydrobiopterin content in rat skeletal muscle arterioles.衰老会降低大鼠骨骼肌小动脉中内皮依赖性血管舒张功能和四氢生物蝶呤含量。
J Physiol. 2008 Feb 15;586(4):1161-8. doi: 10.1113/jphysiol.2007.147686. Epub 2007 Dec 6.
2
Arginase: a critical regulator of nitric oxide synthesis and vascular function.精氨酸酶：一氧化氮合成与血管功能的关键调节因子。
Clin Exp Pharmacol Physiol. 2007 Sep;34(9):906-11. doi: 10.1111/j.1440-1681.2007.04638.x.
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Mechanisms for the role of tetrahydrobiopterin in endothelial function and vascular disease.四氢生物蝶呤在内皮功能和血管疾病中的作用机制。
Clin Sci (Lond). 2007 Jul;113(2):47-63. doi: 10.1042/CS20070108.
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Acute ascorbate supplementation alone or combined with arginase inhibition augments reflex cutaneous vasodilation in aged human skin.单独补充急性抗坏血酸盐或联合精氨酸酶抑制可增强老年人皮肤的反射性皮肤血管舒张。
Am J Physiol Heart Circ Physiol. 2006 Dec;291(6):H2965-70. doi: 10.1152/ajpheart.00648.2006. Epub 2006 Aug 11.
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Tetrahydrobiopterin augments endothelium-dependent dilatation in sedentary but not in habitually exercising older adults.四氢生物蝶呤可增强久坐不动的老年人而非经常锻炼的老年人的内皮依赖性舒张功能。
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