• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

超声乳化术不会诱发新生血管性年龄相关性黄斑变性。

Phacoemulsification does not induce neovascular age-related macular degeneration.

作者信息

Baatz Holger, Darawsha Raed, Ackermann Hanns, Scharioth Gábor B, de Ortueta Diego, Pavlidis Mitrofanis, Hattenbach Lars O

机构信息

Recklinghausen Eye Centre, Recklinghausen, Germany.

出版信息

Invest Ophthalmol Vis Sci. 2008 Mar;49(3):1079-83. doi: 10.1167/iovs.07-0557.

DOI:10.1167/iovs.07-0557
PMID:18326733
Abstract

PURPOSE

To investigate whether cataract surgery by phacoemulsification induces progression of early age-related macular degeneration (AMD) to neovascular AMD.

METHODS

Retrospective case-control study. Included were consecutive patients who had undergone phacoemulsification from January 2000 to February 2006 at the Recklinghausen Eye Centre, who had a preexisting diagnosis of early AMD and who were followed up for at least 1 year after surgery (n = 1152 eyes of 696 patients). The control group comprised phakic patients diagnosed with early AMD from January 2000 to February 2006, who did not undergo eye surgery and were followed up for at least 1 year (n = 334 eyes of 202 patients).

RESULTS

At baseline, control eyes had significantly better visual acuity than those of patients who were going to have cataract surgery (0.30/0.35 +/- 0.34 vs. 0.40/0.49 +/- 0.34, respectively; median/mean +/- SD; P < 0.001, Mann-Whitney rank sum test). After 1 year, visual acuity in the control group was worse than in surgical eyes (0.30/0.39 +/- 0.38 vs. 0.20/0.26 +/- 0.30, respectively; median/mean +/- SD; P < 0.001, Mann-Whitney rank sum test). In the cataract surgery group, neovascular AMD developed in 28 (2.43%) of 1152 eyes in the first postoperative year. In the control group, it developed in 6 (1.74%) of 344 eyes within 1 year. There was no significant difference between the groups in the incidence of neovascular AMD (P = 0.57, odds ratio 1.30, 95% CI 0.52-3.24, logistic regression analysis, adjusted for age and baseline visual acuity).

CONCLUSIONS

The results indicate that cataract surgery in eyes with early AMD is not a causative factor in neovascular AMD.

摘要

目的

研究白内障超声乳化手术是否会促使早期年龄相关性黄斑变性(AMD)进展为新生血管性AMD。

方法

回顾性病例对照研究。纳入2000年1月至2006年2月在雷克林豪森眼科中心接受超声乳化手术、术前已诊断为早期AMD且术后至少随访1年的连续患者(696例患者的1152只眼)。对照组包括2000年1月至2006年2月诊断为早期AMD、未接受眼部手术且至少随访1年的有晶状体眼患者(202例患者的334只眼)。

结果

基线时,对照组眼的视力显著优于即将接受白内障手术患者的眼(分别为0.30/0.35±0.34与0.40/0.49±0.34;中位数/平均值±标准差;P<0.001,曼-惠特尼秩和检验)。1年后,对照组的视力比手术眼差(分别为0.30/0.39±0.38与0.2 /0.26±0.30;中位数/平均值±标准差;P<0.001,曼-惠特尼秩和检验)。在白内障手术组中,1152只眼中有28只(2.43%)在术后第一年发生了新生血管性AMD。在对照组中,344只眼中有6只(1.74%)在1年内发生了新生血管性AMD。两组间新生血管性AMD的发生率无显著差异(P = 0.57,优势比1.30,95%可信区间0.52 - 3.24,逻辑回归分析,校正年龄和基线视力)。

结论

结果表明,早期AMD患者的白内障手术不是新生血管性AMD的致病因素。

相似文献

1
Phacoemulsification does not induce neovascular age-related macular degeneration.超声乳化术不会诱发新生血管性年龄相关性黄斑变性。
Invest Ophthalmol Vis Sci. 2008 Mar;49(3):1079-83. doi: 10.1167/iovs.07-0557.
2
Is pseudophakia a risk factor for neovascular age-related macular degeneration?人工晶状体植入术是新生血管性年龄相关性黄斑变性的危险因素吗?
Invest Ophthalmol Vis Sci. 2007 Apr;48(4):1472-5. doi: 10.1167/iovs.06-0766.
3
[Should patients with age-related macular degeneration have cataract surgery?].年龄相关性黄斑变性患者应该接受白内障手术吗?
J Fr Ophtalmol. 2004 Nov;27(9 Pt 2):3S87-92.
4
The course of age-related macular degeneration following bilateral cataract surgery.双侧白内障手术后年龄相关性黄斑变性的病程。
Ophthalmic Surg Lasers. 1998 Apr;29(4):286-94.
5
[Comparative assessment of the course of age-related macular degeneration in patients after phacoemulsification cataract surgery with implantation of AcrySof Natural SN 60 at and AcrySof SA 60 at lenses].[白内障超声乳化吸除术联合植入AcrySof Natural SN 60和AcrySof SA 60人工晶状体患者年龄相关性黄斑变性病程的比较评估]
Ann Acad Med Stetin. 2007;53 Suppl 1:43-7; discussion 47-8.
6
Long-term visual outcome after cataract surgery: comparison of healthy eyes and eyes with age-related macular degeneration.白内障手术后的长期视力结果:与年龄相关性黄斑变性眼相比的健康眼。
J Cataract Refract Surg. 2012 Mar;38(3):409-14. doi: 10.1016/j.jcrs.2011.09.041. Epub 2012 Jan 15.
7
Prophylactic treatment of age-related macular degeneration report number 1: 810-nanometer laser to eyes with drusen. Unilaterally eligible patients.年龄相关性黄斑变性的预防性治疗报告第1号:对有玻璃膜疣的眼睛进行810纳米激光治疗。单侧符合条件的患者。
Ophthalmology. 2006 Apr;113(4):622.e1. doi: 10.1016/j.ophtha.2005.10.066.
8
Capsule complication during cataract surgery: Retinal detachment after cataract surgery with capsule complication: Swedish Capsule Rupture Study Group report 4.白内障手术期间的晶状体囊并发症:伴有晶状体囊并发症的白内障手术后视网膜脱离:瑞典晶状体囊破裂研究组报告4
J Cataract Refract Surg. 2009 Oct;35(10):1699-705. doi: 10.1016/j.jcrs.2009.05.028.
9
Elevated C-reactive protein levels in patients with polypoidal choroidal vasculopathy and patients with neovascular age-related macular degeneration.息肉样脉络膜血管病变患者和新生血管性年龄相关性黄斑变性患者的C反应蛋白水平升高。
Ophthalmology. 2007 Sep;114(9):1722-7. doi: 10.1016/j.ophtha.2006.12.021. Epub 2007 Apr 2.
10
Incidence and functional outcome of phacoemulsification complicated by posterior capsular rupture.白内障超声乳化吸除术并发后囊膜破裂的发生率及功能转归
Klin Oczna. 2009;111(1-3):26-9.

引用本文的文献

1
Blue-light filtering spectacle lenses for visual performance, sleep, and macular health in adults.蓝光滤光眼镜在成人的视觉表现、睡眠和黄斑健康方面的应用。
Cochrane Database Syst Rev. 2023 Aug 18;8(8):CD013244. doi: 10.1002/14651858.CD013244.pub2.
2
Association between Cataract Surgery and Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis.白内障手术与年龄相关性黄斑变性之间的关联:一项系统评价和荟萃分析
J Ophthalmol. 2022 May 5;2022:6780901. doi: 10.1155/2022/6780901. eCollection 2022.
3
Cataract Surgery and the Risk of Developing Late Age-Related Macular Degeneration: The Age-Related Eye Disease Study 2 Report Number 27.
白内障手术与晚期年龄相关性黄斑变性发病风险:年龄相关性眼病研究 2 报告号 27。
Ophthalmology. 2022 Apr;129(4):414-420. doi: 10.1016/j.ophtha.2021.11.014. Epub 2021 Nov 16.
4
Predictive Factors for Long-Term Outcomes of Cataract Surgery in Patients Receiving Active Treatment for Neovascular Age-Related Macular Degeneration.接受新生血管性年龄相关性黄斑变性积极治疗的患者白内障手术长期预后的预测因素
J Clin Med. 2021 Jul 15;10(14):3124. doi: 10.3390/jcm10143124.
5
An observational clinical study of the influence of phacoemulsification on choroidal neovascular membrane activity in age related macular degeneration.一项关于超声乳化白内障吸除术对年龄相关性黄斑变性脉络膜新生血管膜活性影响的临床观察研究。
Eye (Lond). 2022 Jul;36(7):1379-1383. doi: 10.1038/s41433-021-01653-4. Epub 2021 Jun 25.
6
Does Cataract Surgery Improve the Progression of Age-Related Macular Degeneration? A Meta-Analysis.白内障手术会改善年龄相关性黄斑变性的进展吗?一项荟萃分析。
J Ophthalmol. 2020 Sep 27;2020:7863987. doi: 10.1155/2020/7863987. eCollection 2020.
7
Cross-sectional study of the association between cataract surgery and age-related macular degeneration in the era of phacoemulsification in the national health and nutrition examination survey 2005-2008.2005-2008 年全国健康与营养调查中白内障超声乳化术后与年龄相关性黄斑变性的横断面研究。
BMJ Open. 2020 Sep 6;10(9):e032745. doi: 10.1136/bmjopen-2019-032745.
8
Risk factors for progression of age-related macular degeneration.与年龄相关的黄斑变性进展的风险因素。
Ophthalmic Physiol Opt. 2020 Mar;40(2):140-170. doi: 10.1111/opo.12675. Epub 2020 Feb 25.
9
Effect of Phacoemulsification on Visual Acuity and Macular Morphology in Patients with Wet Age-Related Macular Degeneration.超声乳化术对湿性年龄相关性黄斑变性患者视力和黄斑形态的影响。
Med Sci Monit. 2018 Sep 17;24:6517-6524. doi: 10.12659/MSM.909652.
10
Blue-light filtering intraocular lenses (IOLs) for protecting macular health.用于保护黄斑健康的蓝光滤过型人工晶状体
Cochrane Database Syst Rev. 2018 May 22;5(5):CD011977. doi: 10.1002/14651858.CD011977.pub2.