Department of Clinical Sciences/Ophthalmology, Faculty of Medicine, Norrlands University Hospital, Umeå University, Umeå, Sweden.
J Cataract Refract Surg. 2012 Mar;38(3):409-14. doi: 10.1016/j.jcrs.2011.09.041. Epub 2012 Jan 15.
To compare the long-term longitudinal visual acuity outcomes after cataract surgery in eyes with age-related macular degeneration (AMD) at surgery and eyes without comorbidity.
University-based eye clinic.
Longitudinal cohort study.
Patients having cataract surgery were evaluated over 1 year. A clinical eye examination and corrected distance visual acuity (CDVA) measurement were performed preoperatively and postoperatively as well as 5 and 10 years postoperatively for eligible patients. The patients were divided into functional groups depending on postoperative signs of macular degeneration and postoperative CDVA.
The study evaluated 810 patients. The rate of CDVA decline with age was faster in AMD patients than in patients without comorbidity. The slope of the visual acuity decline was similar in the 2 subgroups with AMD (almost normal CDVA and reduced CDVA postoperatively). After adjustment for age, there was a mean loss of 2.3 logMAR letters in patients with no comorbidity and 6.4 letters in patients with AMD at surgery for each decade of increasing age. More than 75% of AMD patients had better CDVA 10 years after surgery than before surgery.
Patients with signs of AMD at cataract surgery had a longitudinally worse visual outcome than patients without clinical signs of AMD. However, there is no reason to discourage patients with concurrent visually significant cataract and AMD from having surgery because most AMD patients had better CDVA 10 years after surgery than before surgery.
Neither author has a financial or proprietary interest in any material or method mentioned.
比较年龄相关性黄斑变性(AMD)患者与无合并症患者白内障术后的长期纵向视力结果。
以大学为基础的眼科诊所。
纵向队列研究。
对接受白内障手术的患者进行为期 1 年的评估。在术前、术后以及术后 5 年和 10 年对符合条件的患者进行临床眼部检查和矫正远视力(CDVA)测量。根据术后黄斑变性和术后 CDVA 将患者分为功能组。
本研究共评估了 810 名患者。AMD 患者的 CDVA 随年龄下降的速度快于无合并症患者。AMD 患者的两个亚组(术后几乎正常 CDVA 和降低的 CDVA)的视力下降斜率相似。调整年龄后,无合并症患者每增加 10 年,平均损失 2.3 个 logMAR 字母,AMD 患者手术时损失 6.4 个字母。超过 75%的 AMD 患者术后 10 年的 CDVA 优于术前。
在白内障手术时出现 AMD 迹象的患者的纵向视力结果比没有临床 AMD 迹象的患者差。然而,没有理由劝阻同时患有视力显著白内障和 AMD 的患者进行手术,因为大多数 AMD 患者术后 10 年的 CDVA 优于术前。
两位作者均无任何物质或方法的财务或所有权利益。