1995年至2002年芬兰75岁及以上人群的冠心病事件：芬兰心肌梗死病因研究（FINAMI研究）

Coronary events in persons aged 75 years or older in Finland from 1995 to 2002: the FINAMI study.

作者信息

Koukkunen Heli, Salomaa Veikko, Lehto Seppo, Ketonen Matti, Immonen-Räihä Pirjo, Lehtonen Aapo, Havulinna Aki, Kesäniemi Y Antero, Pyörälä Kalevi

机构信息

Department of Medicine, Kuopio University Hospital, Kuopio, Finland.

出版信息

Am J Geriatr Cardiol. 2008 Mar-Apr;17(2):78-86.

PMID:18326953

Abstract

The authors used population-based myocardial infarction (MI) register data to examine trends in incidence, case fatality, treatment strategies of MI, and coronary heart disease (CHD) mortality in persons aged 75 to 99 years in 4 areas of Finland during 1995 through 2002. This age group contributed 53% (n=13,977) of all CHD events, and 65% occurred in women. CHD mortality declined among men annually by 3.5% and 1.0% in the 75- to 84-year-old and 85- to 99-year-old age groups, respectively. Among women, it declined by 2.2% per year in the 75- to 84-year-old age group but increased by 1.3% per year in the 85- to 99-year-old age group. MI attack rate did not change in men but increased significantly in women aged 85 to 99 years. Clinical management of MI in elderly patients was more conservative than in middle-aged patients. In conclusion, one-half of all CHD events occur among persons aged 75 years or older, and elderly patients with CHD represent an increasing burden to the health care system.

摘要

作者利用基于人群的心肌梗死（MI）登记数据，研究了1995年至2002年期间芬兰4个地区75至99岁人群中心肌梗死的发病率、病死率、治疗策略以及冠心病（CHD）死亡率的趋势。该年龄组占所有冠心病事件的53%（n = 13977），且65%的事件发生在女性中。75至84岁年龄组男性的冠心病死亡率每年下降3.5%，85至99岁年龄组男性每年下降1.0%。在女性中，75至84岁年龄组每年下降2.2%，而85至99岁年龄组每年上升1.3%。男性的心肌梗死发病率未发生变化，但85至99岁女性的发病率显著上升。老年患者心肌梗死的临床管理比中年患者更为保守。总之，所有冠心病事件的一半发生在75岁及以上人群中，老年冠心病患者给医疗保健系统带来的负担日益加重。