Ordúñez Pedro, Barceló Alberto, Bernal José L, Espinosa Alfredo, Silva Luis C, Cooper Richard S
Hospital Universitario Dr Gustavo Aldereguía Lima, Cienfuegos, Cuba.
J Hypertens. 2008 Apr;26(4):663-71. doi: 10.1097/HJH.0b013e3282f4309f.
Identifying methods to improve pharmacologic control of elevated blood pressure remains the most urgent challenge in clinical research on hypertension. The probability of having inadequate control varies widely in the population and better understanding of the factors responsible could help to focus treatment strategies.
A population-based community survey of 1475 persons aged 25-74 years, in Cienfuegos, Cuba, was used to identify these factors in a low-resource setting.
While half of women with hypertension were controlled, only one-third of men were receiving successful treatment. Gender differences were not seen, however, among those currently taking medications. The largest burden of hypertension in absolute terms was concentrated in the age range 45-64, emphasizing the heavy burden of uncontrolled high blood pressure that falls on middle-aged men. Race-ethnicity was not a determinant of treatment and control status, nor was inability to obtain medication.
These findings largely confirm the pattern observed in industrialized countries and demonstrate the near-universal challenge confronting primary-care systems in physician-based control of cardiovascular risk factors.
确定改善高血压药物控制的方法仍是高血压临床研究中最紧迫的挑战。血压控制不充分的概率在人群中差异很大,更好地了解相关因素有助于聚焦治疗策略。
在古巴西恩富戈斯,对1475名年龄在25 - 74岁的人群进行了一项基于人群的社区调查,以在资源匮乏的环境中确定这些因素。
虽然一半患有高血压的女性血压得到了控制,但只有三分之一的男性接受了成功治疗。然而,在目前正在服药的人群中未发现性别差异。从绝对数量来看,高血压负担最大的人群集中在45 - 64岁年龄段,这凸显了中年男性面临的未得到控制的高血压的沉重负担。种族不是治疗和控制状况的决定因素,无法获得药物也不是。
这些发现很大程度上证实了在工业化国家观察到的模式,并表明在基于医生的心血管危险因素控制中,初级保健系统面临着几乎普遍存在的挑战。