Schelleman H, Klungel O H, Kromhout D, de Boer A, Stricker B H Ch, Verschuren W M M
Department of Epidemiology & Biostatistics, Erasmus MC, Rotterdam, The Netherlands.
J Hum Hypertens. 2004 May;18(5):317-24. doi: 10.1038/sj.jhh.1001672.
The objective of this study was to determine the prevalence, treatment, and control of hypertension, and the determinants of undertreatment in the Dutch population. The study design was cross-sectional. A population-based survey on cardiovascular disease risk factors in the Netherlands from 1996 to 2002 was the setting of the study. A total of 10 820 men and women, aged 30-59 years, were included in the study. The main outcome measures of the study were: Prevalence of hypertension, treatment, and control of hypertension and determinants of undertreatment of hypertension. Hypertension was defined as: systolic blood pressure (SBP) > or =140 mmHg and/or diastolic blood pressure (DBP) > or =90 mmHg, and/or the use of antihypertensive medication. Treated and controlled hypertension was defined as SBP <140 mmHg and DBP <90 mmHg. Multivariate logistic regression was used to assess the determinants of undertreatment. The prevalence of hypertension in men was 21.4% and in women 14.9%, and 17.9% of the hypertensive men and 38.5% of the hypertensive women were receiving antihypertensive medication. Of the untreated hypertensives, 21.9% of the men and 13.6% of the women were eligible for treatment with antihypertensive medication according to Dutch guidelines. Female gender and the use of cholesterol-lowering medication were associated with an increased chance of being treated. Subjects who were physically active, on a low salt diet, and current smokers had an increased chance of being untreated. Taking cholesterol-lowering medication and no asthma or allergy were factors associated with better control of blood pressure. In conclusion, a considerable proportion of hypertensives were untreated and uncontrolled. Therefore, the detection and control of hypertension in the Netherlands needs to improve. Several groups of hypertensives were identified that need additional care and attention.
本研究的目的是确定荷兰人群中高血压的患病率、治疗情况和控制情况,以及治疗不足的决定因素。研究设计为横断面研究。1996年至2002年荷兰开展的一项基于人群的心血管疾病危险因素调查是本研究的背景。共有10820名年龄在30至59岁之间的男性和女性纳入本研究。本研究的主要结局指标为:高血压患病率、高血压治疗和控制情况以及高血压治疗不足的决定因素。高血压定义为:收缩压(SBP)≥140 mmHg和/或舒张压(DBP)≥90 mmHg,和/或使用抗高血压药物。治疗且血压得到控制的高血压定义为SBP<140 mmHg且DBP<90 mmHg。采用多因素logistic回归评估治疗不足的决定因素。男性高血压患病率为21.4%,女性为14.9%,17.9%的高血压男性和38.5%的高血压女性正在接受抗高血压药物治疗。在未治疗的高血压患者中,根据荷兰指南,21.9%的男性和13.6%的女性符合抗高血压药物治疗条件。女性性别和使用降胆固醇药物与接受治疗的几率增加有关。身体活跃、低盐饮食的受试者以及当前吸烟者未接受治疗的几率增加。服用降胆固醇药物且无哮喘或过敏是血压控制较好的相关因素。总之,相当一部分高血压患者未得到治疗和控制。因此,荷兰高血压的检测和控制需要改善。已确定几组高血压患者需要额外的护理和关注。