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对诊室高血压患者引入家庭血压测量的成本效益分析

Cost-effectiveness of the introduction of home blood pressure measurement in patients with office hypertension.

作者信息

Fukunaga Hidefumi, Ohkubo Takayoshi, Kobayashi Makoto, Tamaki Yuichiro, Kikuya Masahiro, Obara Taku, Nakagawa Miwa, Hara Azusa, Asayama Kei, Metoki Hirohito, Inoue Ryusuke, Hashimoto Junichiro, Totsune Kazuhito, Imai Yutaka

机构信息

Department of Planning for Drug Development and Clinical Evaluation, Tohoku University Graduate School of Pharmaceutical Sciences and Medicine, Sendai, Japan.

出版信息

J Hypertens. 2008 Apr;26(4):685-90. doi: 10.1097/HJH.0b013e3282f42285.

Abstract

OBJECTIVE

Cost-effectiveness of hypertension treatment is an important social and medical issue in Western as well as in Eastern countries, including Japan. Home blood pressure (HBP) measurements have a stronger predictive power for cardiovascular events than casual clinic blood pressure (CBP) measurements. Therefore, the introduction of HBP measurement for the diagnosis and treatment of hypertension should lead to a decrease in medical expenditure. This study presents calculations of the cost savings likely to take place when HBP is implemented for newly detected hypertensive subjects in Japan.

DESIGN AND METHODS

We estimate the cost savings from the perspective of a Japanese healthcare system. To estimate the costs associated with changing from CBP to HBP measurement as the diagnostic tool, we constructed a simulation model using data from the Ohasama study. These calculations are based on current estimates for cost of treatment, prevalence of white-coat hypertension at baseline, and varying the incidence of new hypertension after the initial screening.

RESULTS

When HBP measurement is not incorporated into the diagnostic process, the medical cost is estimated at US$10.89 million per 1000 subjects per 5 years. When HBP measurement is incorporated, the medical cost is estimated at US$9.33 million per 1000 subjects per 5 years. The reductions in medical costs vary from US$674,000 to US$2.51 million per 1000 subjects per 5 years for treatment of hypertension, when sensitivity analysis is performed.

CONCLUSIONS

The introduction of HBP measurement for the treatment of hypertension is very useful for reducing medical costs.

摘要

目的

高血压治疗的成本效益在西方国家以及包括日本在内的东方国家都是一个重要的社会和医学问题。家庭血压(HBP)测量对心血管事件的预测能力比诊所偶测血压(CBP)测量更强。因此,引入HBP测量用于高血压的诊断和治疗应能降低医疗支出。本研究呈现了在日本对新检测出的高血压患者实施HBP测量时可能节省的成本计算。

设计与方法

我们从日本医疗体系的角度估算成本节省情况。为了估算从使用CBP测量改为使用HBP测量作为诊断工具所涉及的成本,我们利用大岛研究的数据构建了一个模拟模型。这些计算基于当前对治疗成本、基线时白大衣高血压患病率以及初次筛查后新高血压发病率变化的估计。

结果

当不将HBP测量纳入诊断过程时,每1000名受试者每5年的医疗成本估计为1089万美元。当纳入HBP测量时,每1000名受试者每5年的医疗成本估计为933万美元。进行敏感性分析时,每1000名受试者每5年治疗高血压的医疗成本降低幅度从67.4万美元到251万美元不等。

结论

引入HBP测量用于高血压治疗对降低医疗成本非常有用。

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