Espinoza-Gómez F, Newton-Sánchez O A, Melnikov V, Virgen-González O, Unrau J
Hospital Regional Universitario, Secretaría de Salud y Bienestar Social del Estado de Colima, Colima, Mexico.
Braz J Infect Dis. 2007 Dec;11(6):603-4. doi: 10.1590/s1413-86702007000600015.
The purpose of the present work was to inform about the first case of meningitis associated to the bacteria Alcaligenes xylosoxidans in a patient with HIV/AIDS. The patient was a 46-year-old male, with the antecedent of have been diagnosed for HIV/ AIDS, who attended in the Hospital Universitario de Colima, Mexico, with fever, shock and meningismus. The study of the cerebrospinal fluid showed pleocytosis, elevated protein levels and hypoglycorrhachia. The culture yielded the presence of Alcaligenes xylosoxidans with sensitivity to ciprofloxacin. After 14 days of treatment with this antibiotic, the patient showed neurologic improvement and was able to continue with his outpatient antiretroviral treatment. The present case shows the importance of the inclusion of this bacterium in the differential diagnosis of the neurological infections in HIV/AIDS patients and emphasizes the importance of considering the bacterial meningitis in this population.
本研究旨在报道首例与木糖氧化产碱杆菌相关的脑膜炎病例，该病例发生在一名艾滋病患者身上。患者为一名46岁男性，此前已被诊断为艾滋病，因发热、休克和颈项强直前往墨西哥科利马大学医院就诊。脑脊液检查显示细胞增多、蛋白水平升高和脑脊液低糖。培养结果显示存在木糖氧化产碱杆菌，对环丙沙星敏感。使用该抗生素治疗14天后，患者神经症状改善，能够继续接受门诊抗逆转录病毒治疗。本病例显示了将这种细菌纳入艾滋病患者神经感染鉴别诊断的重要性，并强调了在这一人群中考虑细菌性脑膜炎的重要性。
