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儿童多系统畸形综合征合并 感染性脑膜炎 1 例报告

A case of meningitis due to in a child with a polymalformative syndrome: a case report.

机构信息

Department of Neurosurgery, University Hospital Center Habib Bourguiba, Sfax, Tunisia.

Department of Obstetrics and Gynecology, University Hospital Center Hedi Chaker, Sfax, Tunisia.

出版信息

Pan Afr Med J. 2021 Jun 15;39:124. doi: 10.11604/pamj.2021.39.124.29794. eCollection 2021.

Abstract

Achromobacter xylosoxidans (AX), also called alcaligenes xylosoxidans, is an aerobic, non-fermenting mobile, gram-negative bacillus which was first isolated in an otorrhea samples in 1971. Infections with these species are quite rare and have often been described in immunocompromised and in premature infants. However, very few cases of meningitis related to AX have been reported in the literature. The authors report a new case of meningitis due to AX in a 45-day-old female infant with polymarformative syndrome meningitis was confirmed by a cyto-biochemical analysis and culture of the cerebrospinal fluid and was treated by antibiotherapy. Hydrocephalus was managed initially with external ventricular drainage followed by a ventriculoperitoneal shunt after rigorous cerebrospinal fluid (CSF) sterilization, with good clinical and radiological outcomes. The prompt and adequate antibiotic adjustment following bacterial isolation has been shown to rapidly modify the clinical outcomes.

摘要

木糖氧化无色杆菌(AX),也称为产碱假单胞菌,是一种需氧、非发酵、移动的革兰氏阴性杆菌,于 1971 年首次从耳溢液样本中分离出来。这些物种的感染非常罕见,通常发生在免疫功能低下和早产儿中。然而,文献中很少有 AX 引起的脑膜炎病例报道。作者报告了一例新的脑膜炎病例,该病例发生在一名 45 天大的女性婴儿中,该婴儿患有多形性综合征脑膜炎,通过细胞生化分析和脑脊液培养证实,并通过抗生素治疗。脑积水最初通过外部脑室引流进行管理,然后在严格的脑脊液(CSF)消毒后进行脑室-腹腔分流,临床和影像学结果良好。细菌分离后及时和充分的抗生素调整已被证明可以迅速改变临床结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a448/8418177/f654a97be462/PAMJ-39-124-g001.jpg

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