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[Changes in collagen biosynthesis in patients with hip joint replacement surgery and reoperation].

作者信息

Becvár R, Myllylä R, Krbec M, Cech O, Adam M

机构信息

Výzkumný ústav chorob revmatických, Praha.

出版信息

Acta Chir Orthop Traumatol Cech. 1991 May;58(3):178-84.

PMID:1832808
Abstract

The authors investigated the intensity of collagen synthesis in patients subjected to operation or re-operation of a total endoprosthesis of the hip joint. The patients suffered from osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. The authors assessed the activity of collagen glucosyl transferase (S-GGT) and the concentration of the N-terminal propeptide procollagen type III by two methods (S-Pro III-N-P and S-Fab) in serum before and after operation. A significant rise of S-GGT and S-Fab, as compared with controls, occurred only after operation while S-Pro III-N-P was elevated already before operation. S-GGT did not differ before and after operation, while N-propeptide concentration rose when either method was used.

摘要

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