Ibáñez M, Cortina B, Gómez V, Alvaro-Gracia J M, Reina T, Castañeda S
Services of Rheumatology, Hospital Universitario de la Princesa, Madrid, Spain.
Clin Exp Rheumatol. 2008 Jan-Feb;26(1):133-5.
Primary multifocal osseous lymphoma is a rare and poorly recognized entity. Here, we present an instructive case of a young man who, six years after a local contusion of the left ankle, developed a painful polylobulated large soft tissue mass. This mass turned out to have arisen from the transformation of a centro follicular non-Hodgkin's lymphoma into a diffuse large B-cell lymphoma involving the calcaneus, talus, cuboid and navicular bones. The diagnostic difficulties as well as the implications of this aggressive transformation are highlighted here.
