急性肝衰竭作为低度非霍奇金淋巴瘤转化为大细胞淋巴瘤的初始表现。

Acute liver failure as initial manifestation of low-grade non-Hodgkin's lymphoma transformation into large-cell lymphoma.

作者信息

Yeshurun M, Isnard F, Garderet L, Rambeloarisoa J, Prevot S, Carbonell N, Najman A

机构信息

Service des maladies du sang, Hopital Saint-Antoine, Paris, France.

出版信息

Leuk Lymphoma. 2001 Jul;42(3):555-9. doi: 10.3109/10428190109064617.

DOI:10.3109/10428190109064617

PMID:11699425

Abstract

Acute liver failure as an initial manifestation of primary non-Hodgkin's lymphoma is a rare phenomenon with a grim prognosis. We report for the first time on a patient with a history of follicular lymphoma in complete remission, presenting fulminant liver failure due to massive liver infiltration by transformed lymphoma cells and portal vein thrombosis, as an initial manifestation of transformation into large-cell lymphoma.

摘要

急性肝衰竭作为原发性非霍奇金淋巴瘤的首发表现是一种罕见现象，预后不良。我们首次报告了一名有滤泡性淋巴瘤完全缓解病史的患者，该患者因转化型淋巴瘤细胞大量浸润肝脏和门静脉血栓形成而出现暴发性肝衰竭，这是其转化为大细胞淋巴瘤的首发表现。