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当群体遗传学服务于基因组学:将适应性放回空间和历史背景中。

When population genetics serves genomics: putting adaptation back in a spatial and historical context.

作者信息

Pauwels Maxime, Roosens Nancy, Frérot Hélène, Saumitou-Laprade Pierre

机构信息

Laboratoire de Génétique et Evolution des Populations Végétales, UMR CNRS 8016, Université des Sciences et Technologies de Lille - Lille1, F-59655 Villeneuve d'Ascq Cedex, France.

出版信息

Curr Opin Plant Biol. 2008 Apr;11(2):129-34. doi: 10.1016/j.pbi.2008.01.005. Epub 2008 Mar 7.

DOI:10.1016/j.pbi.2008.01.005
PMID:18329331
Abstract

Recent advances in molecular biology have opened new perspectives for the study of plant adaptation, especially at the intraspecific level. Nowadays, scientists employing -omic results in multiple scientific fields can be optimistic of their chances of revealing mechanisms involved in adaptive population divergence. However, the investment required by integrative studies greatly reduces the number of experiments that can be performed. In this context, a comprehensive choice of accessions under study is crucial. We maintain this choice could be appreciably enlightened by population genetics because it helps putting adaptive population divergence in a spatial and historical context. As an example, we highlight the usefulness of knowledge about population genetic structure in the integrative study of metal tolerance in Arabidopsis halleri.

摘要

分子生物学的最新进展为植物适应性研究开辟了新的视角,尤其是在种内水平上。如今,在多个科学领域运用 “组学” 结果的科学家们,对揭示适应性种群分化所涉及的机制充满信心。然而,综合研究所需的投入大大减少了能够开展的实验数量。在此背景下,对研究中所选用材料的全面选择至关重要。我们认为,种群遗传学能够显著地为这一选择提供指导,因为它有助于将适应性种群分化置于空间和历史背景之中。例如,我们强调了种群遗传结构知识在拟南芥金属耐受性综合研究中的作用。

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