HIV 相关的杆状体肌病：静脉注射免疫球蛋白疗法在两名 HIV/AIDS 患者中的作用

HIV-associated nemaline rod myopathy: role of intravenous immunoglobulin therapy in two persons with HIV/AIDS.

作者信息

de Sanctis Jorgelina T, Cumbo-Nacheli Gustavo, Dobbie David, Baumgartner David

机构信息

Grand Rapids Medical Education and Research Center, Grand Rapids, Michigan, USA.

出版信息

AIDS Read. 2008 Feb;18(2):90-4.

PMID:18330038

Abstract

Nemaline rod myopathy is a rare disease associated with muscle weakness and the presence of rod-shaped structures in the muscle fibers. Various acquired conditions have been associated with slow progressing presentations during adulthood. Several cases have been diagnosed in adults with HIV infection. The use of intravenous immunoglobulin (IVIG) has not been previously described for the treatment of these patients. We report the cases of 2 patients with HIV-related nemaline rod myopathy who successfully responded to IVIG therapy.

摘要

杆状体肌病是一种罕见疾病，与肌肉无力以及肌纤维中存在杆状结构有关。各种后天性疾病与成年期进展缓慢的症状相关。已有数例在成年HIV感染者中被诊断出该病。此前尚未有关于使用静脉注射免疫球蛋白（IVIG）治疗这些患者的描述。我们报告了2例HIV相关杆状体肌病患者成功接受IVIG治疗的病例。