Rowland L P
Neurological Institute, Columbia University Medical Center, New York, NY 10032, USA.
Acta Myol. 2011 Jun;30(1):29-31.
The human immunodeficiency virus (HIV) causes diverse disorders of the brain, spinal cord and peripheral nerves. Rarely, polymyositis and myoglobinuria are seen. Two other neuromuscular syndromes in people with HIV antibodies are nemaline myopathy and bibrachial amyotrophic diplegia, a form of motor neuron disease. The associations between these diseases and the possibility that HIV infection could be a risk factor for either amyotrophic lateral sclerosis (ALS) itself or other motor neuron diseases are investigated.
人类免疫缺陷病毒(HIV)可引发大脑、脊髓和周围神经的多种病症。罕见情况下,会出现多发性肌炎和肌红蛋白尿。在有HIV抗体的人群中,另外两种神经肌肉综合征是杆状体肌病和双臂肌萎缩性双侧瘫,后者是运动神经元病的一种形式。对这些疾病之间的关联以及HIV感染可能是肌萎缩侧索硬化症(ALS)本身或其他运动神经元疾病的风险因素的可能性进行了研究。