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梨状窝癌对侧淋巴结转移的临床病理研究

[Clinico-pathological study of contralateral lymph node metastasis in pyriform sinus carcinoma].

作者信息

Guan Chao, Liu Bin, Ji Wenyue

机构信息

Department of Otolaryngology, First Affiliated Hospital of China Medical University, Shenyang, 110001, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2007 Dec;21(24):1132-3.

Abstract

OBJECTIVE

To study the related factors of contralateral lymph node metastasis in pyriform sinus carcinoma.

METHOD

Fifty-three patients with pyriform sinus carcinoma underwent simultaneous neck dissection from Oct. 1993 to Oct. 1999 were collected. Transparent lymph node selection and continuous slicing method were used on the postoperative specimens to observe the status of cervical lymph node metastasis. The relationship between contralateral lymph node metastasis and clinico-pathological factors, ipsilateral neck metastatic status were analyzed by the follow-up data.

RESULT

Cervical lymph node metastatic rate was 79.2% in 53 patients with pyriform sinus carcinoma. Contralateral cervical lymph node metastatic rate was 35.8%. Contralateral neck metastasis was closely related with clinical N stage, cell differentiation, fused metastasis and extracapsular spread of ipsilateral neck.

CONCLUSION

Contralateral neck dissection should be undertaken in patients with N2,3, moderate and low cell differentiation, or fused fused metastasis and extracapsular spread of ipsilateral neck.

摘要

目的

探讨梨状窝癌对侧淋巴结转移的相关因素。

方法

收集1993年10月至1999年10月期间行同期颈清扫术的53例梨状窝癌患者。术后标本采用透明淋巴结选择及连续切片法观察颈部淋巴结转移情况。通过随访资料分析对侧淋巴结转移与临床病理因素、同侧颈部转移状况的关系。

结果

53例梨状窝癌患者颈部淋巴结转移率为79.2%。对侧颈部淋巴结转移率为35.8%。对侧颈部转移与临床N分期、细胞分化、融合转移及同侧颈部包膜外扩散密切相关。

结论

N2、3期、细胞中低分化、或同侧颈部有融合转移及包膜外扩散的患者应行对侧颈清扫术。

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