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[经面中揭翻入路联合改良上颌骨切除术切除鼻咽血管纤维瘤]

[Resection of nasopharyngeal angiofibroma using by midfacial degloving approach and modified maxillectomy].

作者信息

Sun Wei, Huang Xiaoming, Zheng Yiqing, Peng Jieren, Zou Hua

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, 2rd Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510120, China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2007 Dec;21(24):1134-5, 1139.

Abstract

OBJECTIVE

To explore the feasibility of treatment on angiofibroma patients with stage III, IV by midfacial degloving approach and modified maxillectomy.

METHOD

From Feb. 2001 to Aug. 2004, midfacial degloving approach and modified maxillectomy was used for treating 7 angiofibroma patients with stage III, IV. Using Fisch stage: Five cases were in stage III, 2 cases were stage IV; 2 cases with stage III accepted midfacial degloving approach and modified maxillectomy. Five cases accepted midfacial degloving approach and Le fort I approach (stage III, 3 cases; stage IV, 2 cases). One patient accepted the combined therapy of facial approach and cranium approach. 6 cases accept the embolization of the artery which feed the tumor (2 cases in stage IV, 4 cases in stage III).

RESULT

The blood loss was (600 +/- 324) ml in operation, the blood loss in operation of patients with selective preoperative embolization was (483 +/- 165) ml. The blood loss of one case with no selective preoperative embolization was 1300 ml. The operating time was 129 +/- 22 min. The pathology of 7 cases was nasopharyngeal angiofibroma. For 30 to 72 months follow-up, No tumor recurrence were observed, one case in stage III accepted the selective preoperative embolization got the tumor recurrence 1 year after the surgery. After the second surgery, no tumor recurrence were seen till now.

CONCLUSION

For the patients in stage III, IV, midfacial degloving approach and modified maxillectomy is not only good for radical excision, curtating the operating time and blood loss, but also good for the cosmetic outlook and functional recovery. The selective preoperative embolization has a good significance on reducing the operating blood loss and tumor recurrence rate.

摘要

目的

探讨经面中部揭翻入路联合改良上颌骨切除术治疗Ⅲ、Ⅳ期血管纤维瘤患者的可行性。

方法

2001年2月至2004年8月,采用面中部揭翻入路联合改良上颌骨切除术治疗7例Ⅲ、Ⅳ期血管纤维瘤患者。采用Fisch分期:Ⅲ期5例,Ⅳ期2例;2例Ⅲ期患者接受面中部揭翻入路联合改良上颌骨切除术。5例接受面中部揭翻入路联合Le fort I入路(Ⅲ期3例,Ⅳ期2例)。1例患者接受面部入路与颅骨入路联合治疗。6例患者接受了肿瘤供血动脉栓塞术(Ⅳ期2例,Ⅲ期4例)。

结果

手术出血量为(600±324)ml,术前选择性栓塞患者手术出血量为(483±165)ml。1例未行术前选择性栓塞患者出血量为1300 ml。手术时间为129±22分钟。7例病理均为鼻咽血管纤维瘤。随访30至72个月,未见肿瘤复发,1例Ⅲ期接受术前选择性栓塞患者术后1年肿瘤复发。二次手术后至今未见肿瘤复发。

结论

对于Ⅲ、Ⅳ期患者,面中部揭翻入路联合改良上颌骨切除术不仅有利于根治性切除,缩短手术时间和减少出血量,而且有利于美观和功能恢复。术前选择性栓塞对减少术中出血量和肿瘤复发率有重要意义。

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