Morgenroth K
Institut für Pathologie der Ruhr-Universität Bochum, Berufsgenossenschaftliche Kliniken Bergmannsheil, Bochum.
Pathologe. 2008 May;29(3):214-20. doi: 10.1007/s00292-008-0999-x. Epub 2008 Mar 12.
Odontogenic cysts form a group of diseases whose origin is linked to the persistence of epithelium resulting from the complex embryonic development of the teeth and jaws within the connective tissue. Inflammatory reactions of the surrounding area of the persisting odontogenic epithelium accompany epithelium proliferation, which leads to the development of a gradually expanding cavity that supersedes the surrounding structure. The correlation between activity of the inflammatory reaction and the development of the epithelial proliferation results in a relatively broad variation of histological features of the cyst wall. Since classification of cyst forms depends on their topographical features, clinical information on the classification of variations is urgently needed. For the classification of their clinical course of development and, in particular, in order to differentiate them from cystic odontogenic tumors of the jaw region, a histological examination of cyst wall tissue is necessary, all the more so since the development of a carcinoma deriving from the odontogenic epithelium has only been described in very few cases.
牙源性囊肿是一组疾病,其起源与结缔组织内牙齿和颌骨复杂胚胎发育所导致的上皮组织持续存在有关。持续存在的牙源性上皮周围区域的炎症反应伴随上皮增殖,这导致逐渐扩大的腔隙形成,该腔隙取代周围结构。炎症反应的活性与上皮增殖的发展之间的相关性导致囊肿壁的组织学特征有相对广泛的变化。由于囊肿形式的分类取决于其地形特征,因此迫切需要有关变异分类的临床信息。为了对其临床发展过程进行分类,特别是为了将它们与颌骨区域的囊性牙源性肿瘤区分开来,有必要对囊肿壁组织进行组织学检查,更何况源自牙源性上皮的癌的发展仅在极少数病例中被描述过。