Chiarini L, Lo Russo L, Figurelli S, Procacci P, Rubini C, Lo Muzio L
Department of Dentistry and Surgery, Faculty of Medicine, University of Modena, Modena, Italy.
Aesthetic Plast Surg. 2008 May;32(3):560-2. doi: 10.1007/s00266-008-9136-8. Epub 2008 Mar 11.
Nodular fasciitis is an uncommon tumor-like fibroblastic proliferation that occurs rarely in the head and neck region. A new case of nodular fasciitis occurring in the cheek of a 56-year-old woman is reported. The case was characterized by dental trauma preceding the appearance of the lesion (extraction of tooth 35). Histologically, the lesion consisted of proliferating fibroblasts and myofibroblasts presenting clinically as a rapidly growing subcutaneous nodule. A conservative surgical excision with curettage is the treatment of choice, and the lesion usually does not exhibit a tendency to recur. The clinical relevance of this condition relies on the fact that both the disorder and its surgical treatment may cause tissue distortion resulting in aesthetic compromise. Furthermore, it needs to be differentiated from malignancy due to its very rapid growth, its rich cellularity, and its high mitotic activity. Both of these aspects, i.e. aesthetic implications and differential diagnosis, have been discussed.
结节性筋膜炎是一种罕见的肿瘤样纤维母细胞增生,很少发生于头颈部区域。本文报告了一例发生在一名56岁女性脸颊的结节性筋膜炎新病例。该病例的特点是在病变出现之前有牙齿外伤史(拔除35号牙)。组织学上,病变由增生的纤维母细胞和平滑肌纤维母细胞组成,临床上表现为快速生长的皮下结节。保守性手术切除并刮除是首选治疗方法,该病变通常无复发倾向。这种疾病的临床相关性在于,该病症及其手术治疗都可能导致组织变形,从而影响美观。此外,由于其生长非常迅速、细胞丰富且有高有丝分裂活性,需要与恶性肿瘤相鉴别。本文对美观影响和鉴别诊断这两个方面都进行了讨论。