Ratajska A, Gawlik Z, Fiejka E
Department of Pathological Anatomy, Medical Academy of Warsaw, Poland.
Experientia. 1991 Sep 15;47(9):964-9. doi: 10.1007/BF01929893.
We studied the distribution of the extracellular matrix proteins fibronectin (FN) and laminin (LM) in the hypertrophied hearts of spontaneously hypertensive rats (SHR), using an immunofluorescence method with specific antibodies. The immunohistochemical reaction was positive in the cytoplasm of some hypertrophied cardiomyocytes. The results showed that FN and LM can be used as markers for tunnels, i.e. intracardiocytic invaginations of the sarcolemma. The tunnels observed contained capillaries.
我们使用特异性抗体免疫荧光法，研究了自发性高血压大鼠（SHR）肥厚心脏中细胞外基质蛋白纤连蛋白（FN）和层粘连蛋白（LM）的分布。免疫组化反应在一些肥厚心肌细胞的细胞质中呈阳性。结果表明，FN和LM可作为隧道的标志物，即肌膜的细胞内陷。观察到的隧道中含有毛细血管。
