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通过锐性解剖进行子宫内膜异位症的保守性腹腔镜切除:再次手术及疾病持续或复发的生命表分析

Conservative laparoscopic excision of endometriosis by sharp dissection: life table analysis of reoperation and persistent or recurrent disease.

作者信息

Redwine D B

机构信息

St. Charles Medical Center, Bend, Oregon 97701.

出版信息

Fertil Steril. 1991 Oct;56(4):628-34. doi: 10.1016/s0015-0282(16)54591-9.

Abstract

OBJECTIVE

To determine the long-term outcome after laparoscopic excision of endometriosis.

DESIGN

This longitudinal unmatched study evaluated surgical outcome using follow-up questionnaires and evaluation of reoperations with results presented in life table format.

SETTING

Surgery was performed by a private practitioner at a referral center.

PATIENTS

All 359 patients undergoing laparoscopic excision of endometriosis between December 12, 1980, and March 31, 1990, were studied.

INTERVENTIONS

Endometriosis, including deeply invasive disease, was completely excised laparoscopically using 3-mm scissors and graspers. Adjunctive medical therapy was not used.

MAIN OUTCOME MEASURES

Extent of disease present at reoperation and quarterly rates of reoperation and recurrent/persistent disease are used as indicators of efficacy of surgery.

RESULTS

Interval rates of reoperation and recurrence/persistence of disease and extent or invasiveness of disease when found at reoperation did not increase with the passage of time after surgery. The maximum cumulative rate of recurrent or persistent disease was 19%, achieved in the 5th postoperative year.

CONCLUSION

Laparoscopic excision of endometriosis results in a low rate of minimal persistent/recurrent disease. The natural history of endometriosis after surgery suggests a rather static nature of the disease.

摘要

目的

确定腹腔镜切除子宫内膜异位症后的长期结局。

设计

这项纵向非配对研究使用随访问卷评估手术结局,并对再次手术进行评估,结果以生命表形式呈现。

地点

手术由一家转诊中心的私人执业医生进行。

患者

研究了1980年12月12日至1990年3月31日期间接受腹腔镜切除子宫内膜异位症的所有359例患者。

干预措施

使用3毫米剪刀和抓钳通过腹腔镜完全切除子宫内膜异位症,包括深部浸润性疾病。未使用辅助药物治疗。

主要结局指标

再次手术时存在的疾病范围以及再次手术和复发/持续性疾病的季度发生率用作手术疗效指标。

结果

再次手术时疾病的再次手术间隔率、复发/持续率以及疾病的范围或侵袭性并未随着手术后时间的推移而增加。术后第5年达到的复发或持续性疾病的最大累积率为19%。

结论

腹腔镜切除子宫内膜异位症导致最小的持续性/复发性疾病发生率较低。手术后子宫内膜异位症的自然病程表明该疾病具有相当稳定的性质。

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