Menon Rukmini, Bushnell Cheryl D
Department of Neurology, Wake Forest University Health Sciences, Winston-Salem, NC, USA.
Neurologist. 2008 Mar;14(2):108-19. doi: 10.1097/NRL.0b013e3181663555.
Many women who suffer from migraine and tension-type headaches (TTHs) have an improvement in the frequency of these headaches during pregnancy. At the same time pregnancy predisposes women to a number of potentially life-threatening conditions which can present with headache. Accurate diagnosis and treatment of headache during pregnancy is essential.
The primary objectives of this review are to: (1) Summarize the natural history of primary headache disorders, including migraine, tension-type, and cluster headaches during pregnancy, as well as the impact of migraine on pregnancy outcomes and complications.(2) Summarize the therapeutic options and strategies for managing headaches in pregnancy and (3) Discuss the causes of secondary headaches and the diagnostic evaluation for new onset headache during pregnancy.
Primary headache disorders, in particular TTHs and migraines, generally improve during pregnancy. However the frequency of improvement varies greatly. Because the pathophysiology of both migraines and TTHs is poorly understood, this limits our ability to predict improvement. Future research should be focused on headache pathophysiology and the effect of ovarian hormones and the pregnant state on headache pathogenesis.
许多患有偏头痛和紧张型头痛(TTH)的女性在孕期这些头痛的发作频率会有所改善。与此同时,怀孕使女性易患一些可能危及生命的疾病,这些疾病可能表现为头痛。孕期头痛的准确诊断和治疗至关重要。
本综述的主要目的是:(1)总结原发性头痛疾病的自然史,包括孕期的偏头痛、紧张型头痛和丛集性头痛,以及偏头痛对妊娠结局和并发症的影响。(2)总结孕期头痛管理的治疗选择和策略,以及(3)讨论继发性头痛的原因和孕期新发头痛的诊断评估。
原发性头痛疾病,尤其是紧张型头痛和偏头痛,在孕期通常会改善。然而,改善的频率差异很大。由于对偏头痛和紧张型头痛的病理生理学了解甚少,这限制了我们预测改善情况的能力。未来的研究应聚焦于头痛的病理生理学以及卵巢激素和妊娠状态对头痛发病机制的影响。