波那普明对脊髓损伤急性期患者多汗症的治疗
Hyperhidrosis treatment with bornaprine in the acute phase of spinal cord-injured patients.
作者信息
Sergi R, Massone A, Moretto S, Oggerino C, Bertolotto F, Losio L, Ottonello M
机构信息
Department of Rehabilitation, Spinal Cord Injury Unit, Santa Corona Hospital, Pietra Ligure, Savona, Italy.
出版信息
Spinal Cord. 2008 Aug;46(8):571-3. doi: 10.1038/sc.2008.12. Epub 2008 Mar 11.
STUDY DESIGN
Original article.
OBJECTIVE
To test the use of bornaprine in the hyperhidrosis treatment in the acute phase of spinal cord-injured patients.
SETTING
Patients with acute spinal cord lesions in the Spinal Unit of Pietra Ligure, Savona, Italy.
METHOD
In 4 years, 12 patients have been treated, for a maximum period of 75 days, with dosages ranging from 2 to 4 mg day(-1).
RESULTS
All of them reported long-lasting subjective benefits, without side effects, even after the interruption of the therapy.
CONCLUSION
The bornaprine treatment, at 2 or 4 mg day(-1) dosage, has been effective and safe to contrast hyperhidrosis, in the acute phase of spinal cord-injured patients. This positive experience would require additional trials and a larger number of cases to gain a more solid support.
研究设计
原创文章。
目的
测试去甲斑蝥素在脊髓损伤患者急性期多汗症治疗中的应用。
地点
意大利萨沃纳皮埃特拉利古雷脊髓科急性脊髓损伤患者。
方法
4年间，对12例患者进行了治疗，最长治疗期为75天，剂量范围为每日2至4毫克。
结果
所有患者均报告有持久的主观益处，即使在治疗中断后也无副作用。
结论
去甲斑蝥素治疗，剂量为每日2或4毫克，在脊髓损伤患者急性期对抗多汗症有效且安全。这一积极经验需要更多试验和更多病例以获得更有力支持。
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